Welcome to SEVENS database
Computational Biology Research Center (CBRC)
SEVENS summarizes GPCR (G-protein coupled receptor) genes that are identified with high accuracy from 28 eukaryote genomes, by a pipeline integrating such software as a gene finder, a sequence alignment tool, a motif and domain assignment tool, and a transmembrane helix predictor. This treats a larger data space (than that in currently available other databases), which should include not only the expressed sequences but also the newly identified sequences that cannot be detected by in vivo experiments, although they definitely exist on the genome sequence and are just waiting for the opportunity to express their functions.
SEVENS can provides the infrastructure of general information of "GPCR universe" for comparative genomics.
- Makiko Suwa,Yukiteru Ono,Tatsuya Nishizawa,Toshiyuki Sato,Ikuo Okouchi,Toshitaka Kumagai,Masanori Arita,Wataru Fujibuchi,Kiyoshi Asai and Yutaka Akiyama
- Computational Biology Research Center (CBRC),National Institute of Advanced Industrial Science and Technology (AIST), AIST Tokyo Waterfront Bio-IT Research Building, 2-42 Aomi, Koutou-ku, Tokyo 135-0064, JAPAN.
- Shinichi Matsumoto,Shuichi Tsutsumi,Hiroyuki Aburatani
- Genome Science Division, RCAST, Univ. Tokyo, 4-6-1 Komaba,Meguro-ku, Tokyo 153-8904, JAPAN.
We are pleased to acknowledge the use of the BLAST package from NCBI, the SOSUI from Dr. T. Hirokawa, the ALN from Dr. O. Gotoh, the HMMER from Dr. A. Bateman.
Comments or questions to
Recent Revise on 2006/08/15.
© Computational Biology Research Center, AIST, 2006 All Rights Reserved.