CBRC SEVENS






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Previous Ver.
  1.30(2005/05/17)
  1.21(2004/02/06)
  1.20(2003/10/09)

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Welcome to SEVENS database
at
Computational Biology Research Center (CBRC)


Information

SEVENS summarizes GPCR (G-protein coupled receptor) genes that are identified with high accuracy from 28 eukaryote genomes, by a pipeline integrating such software as a gene finder, a sequence alignment tool, a motif and domain assignment tool, and a transmembrane helix predictor. This treats a larger data space (than that in currently available other databases), which should include not only the expressed sequences but also the newly identified sequences that cannot be detected by in vivo experiments, although they definitely exist on the genome sequence and are just waiting for the opportunity to express their functions.
SEVENS can provides the infrastructure of general information of "GPCR universe" for comparative genomics.


Our information
Makiko Suwa,Yukiteru Ono,Tatsuya Nishizawa,Toshiyuki Sato,Ikuo Okouchi,Toshitaka Kumagai,Masanori Arita,Wataru Fujibuchi,Kiyoshi Asai and Yutaka Akiyama

Computational Biology Research Center (CBRC),National Institute of Advanced Industrial Science and Technology (AIST), AIST Tokyo Waterfront Bio-IT Research Building, 2-42 Aomi, Koutou-ku, Tokyo 135-0064, JAPAN.

Shinichi Matsumoto,Shuichi Tsutsumi,Hiroyuki Aburatani

Genome Science Division, RCAST, Univ. Tokyo, 4-6-1 Komaba,Meguro-ku, Tokyo 153-8904, JAPAN.
Database

Genome GPCR No. Large Families
 Homo sapiens 1282    Odorant/olfactory and gustatory receptors
Family 2 (B) receptors
Taste receptor type 2
 Rhesus macaque 1001    Odorant/olfactory and gustatory receptors
Family 2 (B) receptors
Taste receptor type 2
 Mus musculus 2288    Odorant/olfactory and gustatory receptors
Family 3 (C) receptors
Pheromone receptors
 Rattus norvegicus 2286    Odorant/olfactory and gustatory receptors
Family 3 (C) receptors
Pheromone receptors
 Canis familiaris 1402    Odorant/olfactory and gustatory receptors
Family 2 (B) receptors
Chemokines and chemotactic factors receptors
 Gallus gallus 693    Odorant/olfactory and gustatory receptors
Family 2 (B) receptors
Adenosine and adenine nucleotide receptors
 Xenopus tropicalis 2416    Odorant/olfactory and gustatory receptors
Family 3 (C) receptors
Family 2 (B) receptors
 Danio rerio 1093    Odorant/olfactory and gustatory receptors
Trace amine receptors
Family 3 (C) receptors
 Tetraodon nigroviridis 574    Family 2 (B) receptors
Family 3 (C) receptors
Odorant/olfactory and gustatory receptors
 Drosophila melanogaster 216    Drosophila odorant receptors
Family 2 (B) receptors
Family 3 (C) receptors
 Drosophila simulans 212    Drosophila odorant receptors
Family 2 (B) receptors
Family 3 (C) receptors
 Drosophila yakuba 228    Drosophila odorant receptors
Family 2 (B) receptors
Family 3 (C) receptors
 Anopheles gambiae 199    Drosophila odorant receptors
Family 2 (B) receptors
Opsins
 Apis mellifera 73    Family 2 (B) receptors
Family 3 (C) receptors
Opsins
 Bombyx mori 69    Drosophila odorant receptors
Family 2 (B) receptors
Family 3 (C) receptors
 Ciona intestinalis 110    Family 2 (B) receptors
Acetylcholine (muscarinic) receptors
Family fz/smo receptors
 Caenorhabditis elegans 1145    Nematode chemoreceptors
Sra proteins
Sre proteins
 Arabidopsis thaliana 18    Plant MLO receptors
 Oryza sativa 15    Plant MLO receptors
 Dictyostelium discoideum 21    Family 3 (C) receptors
Family 5 receptors
Family fz/smo receptors
 Saccharomyces cerevisiae 6    Archaeal/bacterial/fungal opsin family
Family 4 receptors
 Eremothecium gossypii 3    Family 4 receptors
 Candida glabrate CBS138 6    Archaeal/bacterial/fungal opsin family
Family 4 receptors
 Schizosaccharomyces pombe 3    Family 4 receptors
 Cryptococcus neoformans var JEC21 2    Family 4 receptors
 Encephalitozoon cuniculi 0    High reliable GPCR candidate was not found. But lower reliable GPCR candidates were found.
 Kluyveromyces lactis 3    Family 4 receptors
 Debaryomyces hansenii 5    Family 4 receptors
Archaeal/bacterial/fungal opsin family


Acknowledgement
We are pleased to acknowledge the use of the BLAST package from NCBI, the SOSUI from Dr. T. Hirokawa, the ALN from Dr. O. Gotoh, the HMMER from Dr. A. Bateman.

Comments or questions to m-suwa@aist.go.jp
Recent Revise on 2006/08/15.
AIST
© Computational Biology Research Center, AIST, 2006 All Rights Reserved.