Home Documentation   News   What's SEVENS   Statistics Previous Ver.   1.30(2005/05/17)   1.21(2004/02/06)   1.20(2003/10/09) Links   CBRC   GPCRDB   NCBI   Swiss-Prot   PROSITE   Pfam		Welcome to SEVENS database at Computational Biology Research Center (CBRC) Information SEVENS summarizes GPCR (G-protein coupled receptor) genes that are identified with high accuracy from 28 eukaryote genomes, by a pipeline integrating such software as a gene finder, a sequence alignment tool, a motif and domain assignment tool, and a transmembrane helix predictor. This treats a larger data space (than that in currently available other databases), which should include not only the expressed sequences but also the newly identified sequences that cannot be detected by in vivo experiments, although they definitely exist on the genome sequence and are just waiting for the opportunity to express their functions. SEVENS can provides the infrastructure of general information of "GPCR universe" for comparative genomics. Our information Makiko Suwa,Yukiteru Ono,Tatsuya Nishizawa,Toshiyuki Sato,Ikuo Okouchi,Toshitaka Kumagai,Masanori Arita,Wataru Fujibuchi,Kiyoshi Asai and Yutaka Akiyama Computational Biology Research Center (CBRC),National Institute of Advanced Industrial Science and Technology (AIST), AIST Tokyo Waterfront Bio-IT Research Building, 2-42 Aomi, Koutou-ku, Tokyo 135-0064, JAPAN. Shinichi Matsumoto,Shuichi Tsutsumi,Hiroyuki Aburatani Genome Science Division, RCAST, Univ. Tokyo, 4-6-1 Komaba,Meguro-ku, Tokyo 153-8904, JAPAN. Database Genome GPCR No. Large Families  Homo sapiens 1282    Odorant/olfactory and gustatory receptors Family 2 (B) receptors Taste receptor type 2  Rhesus macaque 1001    Odorant/olfactory and gustatory receptors Family 2 (B) receptors Taste receptor type 2  Mus musculus 2288    Odorant/olfactory and gustatory receptors Family 3 (C) receptors Pheromone receptors  Rattus norvegicus 2286    Odorant/olfactory and gustatory receptors Family 3 (C) receptors Pheromone receptors  Canis familiaris 1402    Odorant/olfactory and gustatory receptors Family 2 (B) receptors Chemokines and chemotactic factors receptors  Gallus gallus 693    Odorant/olfactory and gustatory receptors Family 2 (B) receptors Adenosine and adenine nucleotide receptors  Xenopus tropicalis 2416    Odorant/olfactory and gustatory receptors Family 3 (C) receptors Family 2 (B) receptors  Danio rerio 1093    Odorant/olfactory and gustatory receptors Trace amine receptors Family 3 (C) receptors  Tetraodon nigroviridis 574    Family 2 (B) receptors Family 3 (C) receptors Odorant/olfactory and gustatory receptors  Drosophila melanogaster 216    Drosophila odorant receptors Family 2 (B) receptors Family 3 (C) receptors  Drosophila simulans 212    Drosophila odorant receptors Family 2 (B) receptors Family 3 (C) receptors  Drosophila yakuba 228    Drosophila odorant receptors Family 2 (B) receptors Family 3 (C) receptors  Anopheles gambiae 199    Drosophila odorant receptors Family 2 (B) receptors Opsins  Apis mellifera 73    Family 2 (B) receptors Family 3 (C) receptors Opsins  Bombyx mori 69    Drosophila odorant receptors Family 2 (B) receptors Family 3 (C) receptors  Ciona intestinalis 110    Family 2 (B) receptors Acetylcholine (muscarinic) receptors Family fz/smo receptors  Caenorhabditis elegans 1145    Nematode chemoreceptors Sra proteins Sre proteins  Arabidopsis thaliana 18    Plant MLO receptors  Oryza sativa 15    Plant MLO receptors  Dictyostelium discoideum 21    Family 3 (C) receptors Family 5 receptors Family fz/smo receptors  Saccharomyces cerevisiae 6    Archaeal/bacterial/fungal opsin family Family 4 receptors  Eremothecium gossypii 3    Family 4 receptors  Candida glabrate CBS138 6    Archaeal/bacterial/fungal opsin family Family 4 receptors  Schizosaccharomyces pombe 3    Family 4 receptors  Cryptococcus neoformans var JEC21 2    Family 4 receptors  Encephalitozoon cuniculi 0    High reliable GPCR candidate was not found. But lower reliable GPCR candidates were found.  Kluyveromyces lactis 3    Family 4 receptors  Debaryomyces hansenii 5    Family 4 receptors Archaeal/bacterial/fungal opsin family Acknowledgement We are pleased to acknowledge the use of the BLAST package from NCBI, the SOSUI from Dr. T. Hirokawa, the ALN from Dr. O. Gotoh, the HMMER from Dr. A. Bateman. Comments or questions to m-suwa@aist.go.jp Recent Revise on 2006/08/15. © Computational Biology Research Center, AIST, 2006 All Rights Reserved.