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at
Computational Biology Research Center(CBRC)


Information

We developed an automated system for discovering seven transmembrane helix receptors (7-TMR) in the various kinds of genome sequences using algorithms of gene finding, sequence search, motif and domain assignment, transmembrane helix prediction and the gene quality refinement. This system is intended to detect sequences of multi-exon or remote homologues that can not be detected by using conventional sequence search tools alone. Using this system, we surveyed the complete genomes of 9 eukaryotes.

Our information
Makiko Suwa,Yukiteru Ono,Toshiyuki Sato,Ikuo Okouchi,Toshitaka Kumagai,Masanori Arita,Wataru Fujibuchi,Kiyoshi Asai and Yutaka Akiyama

Computational Biology Research Center (CBRC),National Institute of Advanced Industrial Science and Technology (AIST), AIST Tokyo Waterfront Bio-IT Research Building, 2-42 Aomi, Koutou-ku, Tokyo 135-0064, JAPAN.

Shinichi Matsumoto,Shuichi Tsutsumi,Hiroyuki Aburatani

Genome Science Division, RCAST, Univ. Tokyo, 4-6-1 Komaba,Meguro-ku, Tokyo 153-8904, JAPAN.
Database

Genome 7-TMR No. Large Families
Homo sapiens 1290    Odorant/olfactory and gustatory receptors,    Family 2 (B) receptors,    Taste receptors
Drosophila melanogaster 252    Drosophila odorant receptors,    Family 2 (B) receptors,    Family 3 (C) receptors
Caenorhabditis elegans 1016    Nematode chemoreceptors,    Sre proteins,    Srg proteins
Plasmodium falciparum 1     
Encephalitozoon cuniculi 0     
Arabidopsis thaliana 21    Plant Mlo receptors
Oryza sativa 28    Plant Mlo receptors
Saccharomyces cerevisiae 6    Archaeal/bacterial/fungal opsin family,    Family 4 receptors (fungal receptors)
Schizosaccharomyces pombe   4    Family 4 receptors (fungal receptors)



Comments or questions to m-suwa@aist.go.jp
Recent Revise on 2005/05/17.
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